Long-form guides, side-effect deep-dives, and protocol comparisons for men’s health. No paid posts. No “transform your life” copy. We write what we’d want to read before making a treatment decision — for ourselves or someone in our family. Browse by category, search by keyword, or read everything we’ve published.
Short-acting injectable testosterone (primarily testosterone cypionate and enanthate) is the most common TRT method in 2025, delivered via intramuscular or subcutaneous injection every 1-2 weeks. While topical gels remain popular, injectables have become the dominant modality in routine U.S. clinical practice due to their efficacy, cost-effectiveness, and patient preference.
TRT typically does not cause erectile dysfunction (ED) when properly administered to hypogonadal men; it usually improves erectile function. However, improper use, particularly supraphysiological dosing or non-medical testosterone use, can suppress natural testosterone production and potentially worsen ED.
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