Reviewed byAHF Editorial TeamUpdated July 2026
America's Most Trusted Men's Health Clinic. Over 400,000 patients served with FDA-approved treatments for testosterone, ED, weight loss, and hair loss.
Modern TRT clinic focused on ease of use and rapid onboarding. Known for their "cream" based topical testosterone.
Clinic Overview & Credentials
Advanced Rejuvenation occupies a particular niche in Sarasota's wellness landscape: a multi-modality integrative clinic where ozone injections, red light therapy, stem cell protocols, and acoustic wave treatments share the same building as more conventional hormone optimization and men's health services. Located on North East Avenue in Sarasota, FL, the practice draws patients who have cycled through standard medical channels without resolution and are looking for something that sits closer to functional or regenerative medicine. Across 61 verified Google reviews spanning late 2019 through early 2026, the clinic holds a 4.7-star average, with 53 of those reviews landing at five stars. The picture that emerges is of a clinic with genuinely devoted patients, a pair of physicians who generate strong personal loyalty, and a staff culture that reviewers describe in notably warm terms.
Of the 61 Google reviews in the dataset, the dominant theme by a significant margin is staff quality, appearing in 40 reviews (65.6 percent). Results-related commentary follows at 44.3 percent (27 reviews), and prescriber quality surfaces in 36.1 percent (22 reviews). Facility impressions appear in 21.3 percent of reviews; wait time and follow-up care each register in under 12 percent. Pricing transparency is mentioned in four reviews, almost always in the context of out-of-pocket costs for treatments not covered by insurance.
The star distribution is heavily skewed toward the top: 53 five-star reviews, three four-star, one three-star, and four one-star reviews. The four one-star reviews represent the only meaningful friction in the dataset, and their concerns are addressed in the honest breakdown section below.
Two physicians are named repeatedly across the review corpus: Dr. John Lieurance and Dr. Alexander Smithers. Both accumulate strong personal endorsements, though their apparent specialties differ. Lieurance is mentioned in the context of neurological concerns, hearing loss protocols, holistic treatment planning, and IV therapy. Smithers appears most frequently in connection with musculoskeletal injections, Prolozone therapy, and joint-related complaints.
I went in with De Quervain's in my left hand and wrist. Dr. Alexander Smithers treated me with Prolozone therapy and what a difference it has made after just a couple of injections. So totally impressed with the staff and Dr. Smithers. Everyone is so kind and helpful. Highly recommend, especially if you want to avoid surgery!
My experience with Dr Leiurance is always wonderful. He takes his time to evaluate, very nice and knowledgeable. His staff is always professional and very nice. He is the only doctor I trust with my health, and would recommend to anyone. Took my son for neurological problems, Dr. John figured out the problems during the first visit, and did several treatments and on my son same visit. The following day, Dr.John followed up asking how my son was doing.
The follow-up care theme, while smaller in volume (9.8 percent, six reviews), is notable for its specificity. Reviewers do not simply say they felt cared for; they describe same-day treatment decisions, next-day physician check-ins, and individualized treatment plans laid out at the first visit.
Advanced Rejuvenation's service menu spans regenerative therapies (stem cell therapy, PRP, Prolozone/ozone therapy), physical modalities (cryotherapy, red light therapy, acoustic wave therapy), hormone-related services (TRT, ED treatment, P-Shot), and brain health programming. The breadth is unusual for a single Sarasota location, and several reviewers explicitly frame this as a differentiator.
What an incredible clinic!! I can't thank Dr. John Lieurance enough for getting me out of pain! I have been to stem cell clinics and regenerative medicine clinics all over the country that couldn't even come close to Advanced Rejuvenation. Anyone dealing with injuries, chronic pain, hearing loss, poor eye sight, fatigue, chronic illness, or just looking to optimize their health must check out Advanced Rejuvenation!
Red light therapy at this clinic is delivered via a system called Lumomed, which at least one reviewer describes in the context of hearing loss and tinnitus treatment. This is an unconventional application of photobiomodulation, and the reviewer in question appropriately notes that evaluation is still in progress.
I just completed several sessions of the Lumomed red light therapy for hearing loss and tinnitus. While it is too soon to fully evaluate, I commend Dr. John Lieurance and his incredible staff for helping clients with all sorts of medical and holistic well-being needs.
PRP and stem cell therapy are mentioned together in at least one review, applied to bilateral shoulder complaints, with the patient reporting outcomes that exceeded expectations. Ozone therapy surfaces under the Prolozone label (ozone combined with procaine and nutrients, injected into joints or soft tissue) and appears to be one of the clinic's more frequently referenced treatments in the musculoskeletal context.
IV therapy is mentioned by name in the comparison-to-alternative theme cluster, with one reviewer describing a protocol called "Luma Blue" in terms that suggest a multi-component infusion session. The clinic's website [source: http://advancedrejuvenation.us/] would be the appropriate place to verify current protocol availability.
In a dataset where 65.6 percent of reviews mention staff quality, the pattern is worth examining closely. Individual staff members named across the reviews include Candace (or Candice), Carly, Bojana, Ami, Tara, Fawn, and Lacey. The consistency with which specific names appear across reviews from different years suggests low staff turnover, at least among the core clinical team.
The sentiment breakdown for staff quality is 39 positive, zero neutral, one negative across 40 reviews. That is an unusually clean signal. For context, prescriber quality carries two negative mentions out of 22 total, and results carry two negatives out of 27. The staff experience is, by the numbers, the most consistently positive dimension of the patient experience at this Sarasota clinic.
Thank you to the doctors, managers and staff and in particular to wonderful and knowledgeable Candace, as well as Carly such a breath of fresh air and Bojana who assists with nurse-based procedures and healing.
What a wonderful clinic. Kind, engaged people. I felt comfortable during the treatment and happy I went.
The facility itself draws positive mentions in 21.3 percent of reviews, with one reviewer specifically noting the physician's personal artwork displayed in the space, describing it as a "meaningful and beautiful practice." This is a detail that speaks to the clinic's aesthetic intentionality, which several reviewers seem to register as part of the overall experience.
The dataset contains four one-star reviews, one three-star review, and three four-star reviews. The four one-star entries represent the primary friction signal. Because the total count of three-star-or-lower reviews is five (meeting the threshold), the concerns from those reviews warrant direct treatment.
The one-star reviews cluster around a few distinct issues: billing or pricing inconsistency (noted in the pricing transparency theme, where one reviewer describes being quoted $100 for a COVID test by phone and charged $125 at the desk), scheduling or communication friction, and in at least one case, dissatisfaction with clinical outcomes or the direction of care. The prescriber quality theme carries two negative mentions, which, while a small fraction of 22 total, suggests that not every patient-physician interaction lands well.
The pricing transparency theme (four reviews, 6.6 percent) is mixed: two positive, one neutral, one negative. The negative instance involves a same-day price discrepancy that the clinic ultimately resolved at the patient's request, but the reviewer flagged the experience as a concern. The positive pricing mentions generally come from patients who felt the out-of-pocket cost was reasonable given the service, or who appreciated the transparency of the consultation process.
One reviewer who gave four stars noted "Many healing modalities" and "great staff" without elaboration, suggesting mild satisfaction rather than friction. The three-star review is not represented in the verbatim excerpts provided, so specific commentary from that review is not available.
The wait time theme contains three negative mentions out of seven total. Given that the clinic appears to operate on a limited schedule (Thursday hours are listed in the source data, though this may not represent the full weekly availability), appointment availability and scheduling predictability may be worth asking about directly before committing to a treatment plan.
Several competitors operate in the Sarasota market with overlapping service profiles, particularly in the hormone optimization and men's health space.
| Clinic | Rating | Review Count | Notable Overlap |
|---|---|---|---|
| Advanced Rejuvenation | 4.7 | 61 | Full regenerative + hormone + brain health menu |
| Gameday Men's Health Sarasota | 5.0 | 258 | TRT, peptide therapy |
| Eros Vitality | 5.0 | 20 | Men's health, sexual health |
| Gapin Institute for Precision Medicine | 4.5 | 23 | Precision medicine, hormone optimization |
| Advanced TRT Clinic | 5.0 | 2 | TRT (very limited review base) |
| Revival Health | 5.0 | 11 | General wellness, limited review base |
A few observations from this comparison. Gameday Men's Health Sarasota carries a 5.0 average across 258 reviews, which is a substantially larger review corpus than any other clinic on this list. Patients whose primary interest is TRT or peptide therapy would find Gameday's review volume a meaningful signal worth examining. Advanced Rejuvenation's 4.7 rating across 61 reviews is credible, but the lower volume means individual outlier reviews carry more statistical weight.
Where Advanced Rejuvenation appears to differentiate is breadth. No other clinic on this list surfaces stem cell therapy, ozone/Prolozone, red light therapy, cryotherapy, brain health programming, and acoustic wave therapy under one roof in Sarasota. For patients managing multiple concerns simultaneously, or for those who have not found resolution through more conventional hormone or men's health clinics, the multi-modality model may be worth the trade-off in review volume.
The comparison-to-alternative theme in the review data (8.2 percent, five reviews) is almost entirely positive, with four of five mentions framing the clinic favorably against prior experiences at other facilities, including other regenerative medicine clinics nationally.
Based strictly on what the review data surfaces, Advanced Rejuvenation in Sarasota appears to be a strong match for patients who are:
The clinic is likely a less ideal fit for patients who:
What is the general patient experience like at the front desk and with clinical staff?
Staff quality is the single most frequently mentioned theme in the review data, appearing in 65.6 percent of all 61 reviews, with 39 positive mentions and one negative. Reviewers consistently name specific staff members across multiple years, suggesting a stable core team. One patient described the experience at reception through to clinical procedures in a single review:
I am grateful to have learned about Advanced Rejuvenation through Michael Jaco, the facility is top notch, from the reception desk with Candice to Dr John who is exceptional along with the other Doctors and staff… I feel confident in the treatment plan that they have laid out for me will be very successful.
The pattern across reviews suggests that the staff culture is not incidental to the experience here. It appears to be a deliberate feature of how the clinic operates.
How do patients describe Dr. John Lieurance?
Dr. Lieurance is the most frequently named practitioner in the review corpus. Reviewers describe him as thorough in evaluation, personally engaged with patients, and willing to follow up after appointments. One reviewer credited him with resolving a neurological concern in a family member during a single visit and noted a follow-up call the next day.
He is the only doctor I trust with my health, and would recommend to anyone. Took my son for neurological problems, Dr. John figured out the problems during the first visit, and did several treatments and on my son same visit. The following day, Dr.John followed up asking how my son was doing. So pleased, he really cares and that makes a big difference.
Two negative mentions appear in the prescriber quality theme, which, while a small fraction, indicates that not every patient interaction is uniformly positive. Prospective patients should consider scheduling a consultation before committing to a multi-session treatment plan.
What about Dr. Alexander Smithers?
Dr. Smithers appears most prominently in reviews related to musculoskeletal and joint complaints. Prolozone therapy (a form of ozone injection combined with other agents, applied to joints and soft tissue) is the treatment most frequently associated with his name in the review data. Reviewers describe notable relief from conditions including De Quervain's tenosynovitis, plantar fasciitis, and arthritic joints.
Dr Smithers is the best!! We are so blessed to have him in ours lives. The staff is so sweet and understanding 💗
The sentiment around Dr. Smithers in the review data is uniformly positive in the excerpts available.
Are treatments covered by insurance?
The pricing transparency theme surfaces this concern directly. Two reviews from 2020 mention out-of-pocket costs for COVID testing at the time, one of which involved a pricing discrepancy at the desk. A separate review from 2020 notes that stem cell and regenerative treatments are "not yet covered by insurance." This is consistent with the broader landscape for regenerative and integrative medicine services in the United States. Patients should expect to pay out-of-pocket for most services offered at this Sarasota clinic and should confirm pricing directly before scheduling.
What can patients expect regarding wait times and scheduling?
The wait time theme appears in 11.5 percent of reviews, with four positive mentions and three negative. One reviewer specifically noted being seen exactly at the scheduled appointment time and contrasted this favorably with other clinics. The source data lists Thursday as the only confirmed operating day, though this may reflect incomplete hours data rather than the full schedule. Patients should verify current availability directly with the clinic [source: http://advancedrejuvenation.us/] or by phone at (941) 330-8553.
How does the clinic approach red light therapy, and for what conditions is it used?
Red light therapy at the clinic is delivered via a system called Lumomed. Reviews mention its use for hearing loss and tinnitus, which is a non-standard application of photobiomodulation. The reviewer who described this treatment appropriately noted that evaluation was still early. The clinic's broader red light therapy offerings are not described in granular detail in the review data, so prospective patients with specific conditions should inquire about the clinical rationale and expected session protocols before beginning.
What is the IV therapy experience like?
IV therapy is mentioned in the comparison-to-alternative theme cluster. One reviewer described a protocol called "Luma Blue" as a multi-step IV experience and reported feeling markedly better afterward. The review frames the clinic explicitly as "the best alternative to big pharma," which signals the patient population this clinic tends to attract. Patients looking for evidence-based, peer-reviewed IV protocols should review the clinic's clinical rationale before proceeding.
I had the most EPIC DAY at Advanced Rejuvenation with Ami (Ami is one of the RNs on staff) last week!! I had the \
How do patients who have tried other regenerative clinics describe Advanced Rejuvenation by comparison?
The comparison-to-alternative theme (8.2 percent, five reviews) skews heavily positive, with four of five mentions favoring the clinic over prior experiences. One reviewer described having visited regenerative and stem cell clinics nationally before arriving in Sarasota and stated that none of those experiences compared favorably. Another described immediate relief from plantar fasciitis after eight months of unsuccessful self-treatment.
For the past 8 months I've lived with plantar fasciitis and thrown tons of money at shoes and gadgets in the hopes I will be able to get back to my life at some point. I found TRT, called Advanced Rejuvenation and was seen the next day and treated with tissue rejuvenation treatment and immediately had relief.
These are patient-reported experiences and should not be read as predictive of outcomes for any individual case.
What do reviews say about PRP and stem cell therapy specifically?
PRP and stem cell therapy appear together in at least one review, applied to bilateral shoulder complaints. The reviewer reported outcomes exceeding expectations. Stem cell therapy is listed as a service on the clinic's website [source: http://advancedrejuvenation.us/], and a 2020 review from a consultation visit notes that the physician had "extensive training in his field and beyond" with respect to stem cell and joint treatments. That same review notes the out-of-pocket cost reality and frames the clinic as a reasonable alternative for patients seeking to avoid surgery or long-term pain medication.
Is the facility environment something patients notice?
Yes. Thirteen reviews (21.3 percent) mention the physical environment, all positively. One reviewer was struck by the physician's personal artwork displayed in the space, describing it as a "meaningful and beautiful practice." Another used the phrase "Many healing modalities" alongside "great staff" as a summary of the experience. The facility appears to be designed with intentionality, which several patients register as part of the overall clinical experience rather than incidental to it.
What is the follow-up care experience like after an initial visit?
Follow-up care appears in six reviews (9.8 percent), with five positive and one negative. The most specific account involves Dr. Lieurance calling a patient the day after treating their son for neurological concerns. Another reviewer described a detailed treatment plan laid out at the first visit, framing this as confidence-building. One reviewer noted that after a single week of TRT treatment for an arthritic knee and shoulder, improvement was already apparent, and they planned to continue care at the clinic.
What should patients know before their first appointment?
Based on the review data, a few practical considerations emerge. First, most services appear to be out-of-pocket, so arriving with a clear sense of budget and priorities is useful. Second, the clinic's model seems to reward patients who engage with the physician's treatment philosophy rather than those seeking a transactional single-session experience. Third, scheduling appears to require advance planning; same-day availability is mentioned in a small number of reviews but does not appear to be a standard feature. Confirming current hours and availability directly with the clinic before planning a visit is advisable.
Review data sourced from 61 verified Google reviews, spanning October 2019 through March 2026. Star distribution: 53 five-star, 3 four-star, 1 three-star, 4 one-star. Average rating: 4.66. All verbatim quotes reproduced exactly as written by reviewers.
This is not a treatment recommendation. It is a directory entry. Any treatment decision belongs with a licensed physician who can examine the patient and evaluate their specific case.
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