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Compounded semaglutide at one of the lowest entry prices in telehealth — async-light intake fits straightforward GLP-1 candidates.
Complete the Hims weight-loss intake — weight history, BMI, medical conditions, GLP-1 contraindications (MTC family history, severe gastroparesis, prior pancreatitis), current medications, target weight, and prior weight-loss attempts. Free async consult is the platform default; most prescriptions are written within 24–72 hours.
Lab order issued for baseline metabolic markers — fasting glucose, HbA1c, lipid panel, thyroid (TSH + free T4), liver enzymes, kidney function. Local LabCorp or Quest draw site visit; results in 2–3 business days. Prescriber reviews labs and either confirms protocol or escalates if anything flags.
First compounded semaglutide shipment lands. Standard start is 0.25mg weekly subcutaneous injection — conservative entry to manage GI tolerance. First month typically produces 2–5 pounds of loss alongside appetite reduction. Side effects (nausea, mild GI upset) peak in the first 2–4 weeks then subside for most patients.
Dose titration to therapeutic range (0.5mg → 1mg → 1.7mg → 2.4mg/week depending on response and tolerance). Average loss at 6 months on therapeutic-dose semaglutide runs 10–15% of starting body weight in responders. Follow-up labs at 12 weeks then quarterly. The hard question at 6 months: how to maintain the loss — Hims continues prescribing at maintenance doses, but the regain risk on full discontinuation is the long-term consideration.
[PeterMD](/online-providers/weight-loss/petermd) and Hims compete on compounded GLP-1 telehealth at similar price points (Hims $199/mo, PeterMD $200–$300/mo depending on dose tier). PeterMD's edge is multi-medication catalog: semaglutide, tirzepatide, and phentermine all available under one prescriber so you can switch medications during treatment if your first protocol underperforms. Hims is semaglutide-focused — if tirzepatide is on your radar, Hims doesn't have it at this price point. AHF rates Hims 4.0 (weight-loss) and PeterMD 4.3 (weight-loss) — gap reflects PeterMD's medication flexibility advantage. Pick Hims if compounded semaglutide at the lowest price is the priority. Pick PeterMD if you want medication-switching flexibility within one provider relationship.
[Marek Health](/online-providers/weight-loss/marek-health) brings premium-concierge GLP-1 prescribing — comprehensive metabolic panels (ApoB, fasting insulin, leptin), deeper clinical-relationship pricing ($300–$600+/mo all-in), more rigorous monitoring cadence. Hims is the volume-optimized mass-market operation at materially lower entry pricing. AHF rates Hims 4.0 and Marek 4.4 (weight-loss). Pick Hims if cost-conscious GLP-1 with appropriate baseline monitoring is enough for your case. Pick Marek if you have layered metabolic factors (insulin resistance, inflammatory markers, integrated hormone considerations) and your budget supports the comprehensive workup.
Yes — Hims operates as a publicly-traded U.S. telehealth platform with licensed physicians prescribing in each state served. Compounded semaglutide is dispensed through 503A/503B compounding pharmacy partners under physician orders. The medication is real, the prescribing process is real, and the legitimacy infrastructure (NYSE: HIMS, $2.35B revenue, public company financial disclosures) is verifiable. The watch points are platform-scale issues (async-rigor at volume, cancellation friction) and the regulatory-shifting landscape for compounded GLP-1s post-FDA-shortage-end, not the legitimacy of the basic operation.
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