From $1.60 · Free consult · 3.2★ on Trustpilot · 45+ States
750 verified reviews
Pay-per-visit marketplace applied to GLP-1 — real clinical encounter with licensed providers (including dermatologists/endocrinologists), broader medication catalog than subscription telehealth.
Browse Sesame's provider marketplace — filter for weight-management specialists, endocrinologists, or GLP-1-experienced providers; compare upfront cash prices for visits ($29 base, $50–$100 typical for weight-management consultations). Book same-day or next-day video visit directly with the provider you choose.
Video visit with the Sesame provider — typically 20–45 minutes for weight-management initial consultations. Discuss weight history, BMI, GLP-1 contraindications (MTC family history, severe gastroparesis, prior pancreatitis), comorbidities, and goals. Provider determines whether to order baseline labs (decision varies by case complexity vs the mass-market no-labs-shortcut) and writes the prescription. Medication shipped to your pharmacy of choice or mail-order.
First medication shipment lands. Standard start is semaglutide 0.25mg/week or tirzepatide 2.5mg/week conservative entry. The advantage of the encounter-based model: if you want clinical advice during the GI-side-effect adjustment period, you can book another $29 visit with the same Sesame provider rather than relying on async support tickets at subscription platforms.
Dose titration to therapeutic range (semaglutide 0.5mg → 1mg → 1.7mg → 2.4mg/week; tirzepatide 5mg → 10mg → 15mg/week). For Sesame patients, titration conversations happen during scheduled clinical encounters with the same provider relationship — vs mass-market subscription model where titration is often async messaging. Average loss at 6 months on therapeutic-dose GLP-1 runs 10–15% of starting body weight in semaglutide responders, 12–18% in tirzepatide responders.
[Hims](/online-providers/weight-loss/hims) is the subscription-async model at $199/mo compounded semaglutide — algorithmically routed intake, set-and-forget refills, lowest mass-market entry tier. Sesame is the pay-per-visit marketplace at $29–$100/visit + $149–$200 prescription pricing — real clinical encounter with licensed providers (often actual endocrinologists or weight-management specialists). Pick Hims if you want frictionless subscription auto-refill at the lowest mass-market subscription cost. Pick Sesame if you want a real clinical encounter (better for cases needing case-specific evaluation, complex metabolic profiles, or non-standard protocols). AHF rates Hims 4.0 and Sesame 4.1 (weight-loss) — narrow gap reflects Sesame's clinical-encounter advantage vs Hims's subscription-convenience advantage.
[PeterMD](/online-providers/weight-loss/petermd) is the subscription telehealth at $200–$300/mo with the multi-medication catalog (semaglutide + tirzepatide + phentermine). Sesame is the pay-per-visit marketplace at $29–$100/visit + $149–$200 prescription. PeterMD's strength is the integrated subscription account if you're also on TRT or ED treatment and want bundled access. Sesame's strength is the real clinical encounter for cases needing clinical judgment and the pay-per-use pricing for intermittent users. AHF rates PeterMD 4.3 and Sesame 4.1 (weight-loss) — gap reflects PeterMD's medication-switching-flexibility-within-one-provider vs Sesame's marketplace-of-specialists approach.
Yes — Sesame is a healthcare marketplace where licensed providers (physicians, NPs, sometimes actual endocrinologists or weight-management specialists) list their services with upfront cash pricing. Patients book directly, pay per visit, and receive prescriptions sent to the pharmacy of their choice. The legitimacy infrastructure is robust — Sesame providers must be licensed and credentialed; the marketplace doesn't prescribe directly, it connects patients with real clinicians. For weight-loss specifically, look for providers who advertise GLP-1 experience or weight-management as a specialty before booking.
Free consultation. Independently reviewed. Board-certified physicians.
Get Free ConsultationSecure telemedicine · HIPAA compliant · Cancel anytime